Evidence-basis for anticoagulants for cerebral sinus venous thrombosis?

Evidence-Basis for Anticoagulants for Cerebral Sinus Venous Thrombosis? To the Editor: The recent case of cerebral sinus venous thrombosis (CSVT) in the US Secretary of State Hillary Clinton brought my attention to articles that lay out the evidence-basis for the use of full dose heparin and oral anticoagulant drugs for CSVT. Unfortunately, articles published in Stroke by investigators from the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT), a large prospective observational study, have failed to report important evidence against the hypothesis that anticoagulants reduce morbidity and mortality of patients with CSVT. The following points have been missed specifically: